{"id":4735,"date":"2024-01-06T03:52:14","date_gmt":"2024-01-05T22:22:14","guid":{"rendered":"https:\/\/adultserviceau.com.au\/blog\/eli-lilly-offers-obesity-drug-directly-to-consumers\/"},"modified":"2024-01-06T03:52:14","modified_gmt":"2024-01-05T22:22:14","slug":"eli-lilly-offers-obesity-drug-directly-to-consumers","status":"publish","type":"post","link":"https:\/\/adultserviceau.com.au\/blog\/eli-lilly-offers-obesity-drug-directly-to-consumers\/","title":{"rendered":"Eli Lilly Offers Obesity Drug Directly to Consumers"},"content":{"rendered":"<p> [ad_1]<br \/>\n<\/p>\n<div data-page=\"1\">\n<section>\n<p>Jan. 5, 2024 \u2014 Eli Lilly, maker of the anti-obesity drug Zepbound, announced this week the launch of <a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/lillydirect.lilly.com\/\"><span>LillyDirect,<\/span><\/a> a direct-to-patient portal, allowing some patients to obtain its drug for as little as $25 a month.<\/p>\n<p><span>The move is seen as a major shift in the way these popular medications can reach patients.\u00a0<\/span><\/p>\n<p><span>For many of the\u00a0<\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.cdc.gov\/obesity\/data\/adult.html\"><span>42 million<\/span><\/a><span> Americans with <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.webmd.com\/obesity\/what-obesity-is\" id=\"05fbd032-44bc-450b-99f0-74562dac6577;medical_reference\">obesity<\/a><span>, weight loss medications such as Wegovy, Saxenda, and the brand-new Zepbound can be a godsend, helping them lose the excess pounds they\u2019ve struggled with for decades or a lifetime.<\/span><\/p>\n<p><span>But getting these medications has been a struggle for many who are eligible. Shortages of the drugs have been one barrier, and costs of up to $1,300 monthly \u2013 the price tag without insurance coverage \u2013 are another hurdle.<\/span><\/p>\n<p><span>But 2024 may be a much brighter year, thanks to Lilly\u2019s new portal as well as other developments:<\/span><\/p>\n<ul>\n<li><span>Insurance coverage on private health plans, while still spotty, may be improving. Federal legislators are fighting a 2003 law that forbids Medicare from paying for the medications when prescribed for obesity.<\/span><\/li>\n<li><span>New research found that semaglutide (Wegovy) can reduce the risk of recurrent strokes and heart attacks as well as deaths from cardiovascular events in those with obesity and preexisting cardiovascular disease (or diseases of the heart and blood vessels), a finding experts said should get the attention of health insurers.<\/span><\/li>\n<\/ul>\n<\/section>\n<section><pagebreak\/>\n<p><span>The medications, also referred to as GLP-1 agonists, work by activating the receptors of hormones (called glucagon-like peptide 1 and others) that are naturally released after eating. That, in turn, makes you feel more full, leading to weight loss of up to 22% for some. The medications are approved for those with a body mass index (BMI) of 30 or a BMI of 27 with at least one other weight-related health condition such as high blood pressure or high cholesterol. The medicines, injected weekly or more often, are prescribed along with advice about a reduced-calorie diet and increased physical activity.<\/span><\/p>\n<p><span><strong>LillyDirect<\/strong><\/span><\/p>\n<p><span>Eli Lilly launched its direct-to-patient portal on Thursday, providing its obesity medicine (as well as diabetes and migraine drugs) direct to the consumer. Patients can access the obesity medicines through the telehealth platform FORM. Patients reach independent telehealth providers, according to Lilly, who can complement a patient\u2019s current doctor or be an alternative to in-patient care in some cases.\u00a0<\/span><\/p>\n<\/section>\n<\/div>\n<div data-page=\"2\">\n<section>\n<p><span>Costs <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.zepbound.lilly.com\/coverage-savings\"><span>vary, depending on coverage,<\/span><\/a><span> but a 1-month or 3-month supply for someone with commercial insurance coverage could be as little as $25 a month; those with an insurance plan that does not cover the drug could pay $550 for a one-month supply, according to Lilly.<\/span><\/p>\n<p>\u00a0<\/p>\n<p><span>Eli Lilly officials did not respond to requests for comment.\u00a0<\/span><\/p>\n<p><span>Some obesity experts welcomed the new service. \u201cAny program that improves availability and affordability of these ground-breaking medications is welcome news for our long-suffering patients,\u201d said Louis Aronne, MD, director of the Comprehensive Weight Control Center at Weill Cornell Medicine in New York City, a long-time obesity researcher.<\/span><\/p>\n<p><span>\u201cIt\u2019s a great move for Lilly to do,\u201d agreed Caroline Apovian, MD, a professor of medicine at Harvard Medical School and co-director of the Center for Weight Management and Wellness at Brigham &amp; Women\u2019s Hospital in Boston, who is also a veteran obesity specialist. \u201cIt is trying to help the accessibility issue and do it responsibly.\u201d\u00a0<\/span><\/p>\n<\/section>\n<section><pagebreak\/>\n<p><span>\u201cThe bottom line is, there is an overwhelming amount of consumer need and desire for these medications and not enough channels [to provide them],\u201d said Zeev Neuwirth, MD, a former executive at Atrium Health who writes about health care trends. \u201cEli Lilly is responding to a market need that is out there and quite honestly continuing to grow.\u201d\u00a0<\/span><\/p>\n<div id=\"em-pullquote-2\" class=\"em-mod-pullquote\" ref=\"em-pullquote-2\">\n<aside data-e2e=\"ia-pull-quote\" id=\"ia-pull-quote\" align=\"left\" class=\"ia-module-container ia-pull-quote left\">\n<blockquote class=\"pq-wrapper\">\n<p class=\"pq-title\">\n\t\t\t\t\t\t\t\t\t\t\t\t\tAny program that improves availability and affordability of these ground-breaking medications is welcome news for our long-suffering patients.\n\t\t\t\t\t\t\t\t\t\t\t\t<\/p>\n<p>\t\t\t\t\t\t\t\t\t\t\t\t<small class=\"pq-description\"><br \/>\n\t\t\t\t\t\t\t\t\t\t\t\t\tLouis Aronne, MD, Weill Cornell Medicine, New York.<br \/>\n\t\t\t\t\t\t\t\t\t\t\t\t<\/small>\n\t\t\t\t\t\t\t\t\t\t\t<\/p><\/blockquote>\n<\/aside><\/div>\n<p><span>There are still concerns and questions, Neuwirth said, \u201cespecially since this is to my knowledge the first of its kind in terms of a pharmaceutical manufacturer directly dispensing medication in this nontraditional way.\u201d<\/span><\/p>\n<p><span>He called for transparency between telehealth providers and the pharmaceutical company to rule out any conflicts of interest.\u00a0<\/span><\/p>\n<p><span>The American College of Physicians, an organization of internal medicine doctors and others, issued a statement expressing concern. Omar T. Atiq, MD, group\u2019s president, said his organization is \u201cconcerned by the development of websites that enable patients to order prescription medications directly from the drugmakers. While information on in-person care is available, this direct-to-consumer approach is primarily oriented around the use of telehealth services to prescribe a drug maker\u2019s products.\u201d<\/span><\/p>\n<\/section>\n<\/div>\n<div data-page=\"3\">\n<section>\n<p><span>The group urged that an established patient-doctor relationship be present, or that care should happen in consultation with a doctor who does have an established relationship (the latter an option offered by Lilly). \u201cThese direct-to-consumer services have the potential to leave patients confused and misinformed about medications.\u201d<\/span><\/p>\n<p><span><strong>Heart Attack, Stroke Reduction Benefits<\/strong><\/span><\/p>\n<p><span>Previous <\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.ahajournals.org\/doi\/10.1161\/CIRCULATIONAHA.122.059595\"><span>research<\/span><\/a><span> has found that the GLP-1 medicines such as Ozempic (semaglutide), which the FDA approved to treat diabetes, also reduce the risk of cardiovascular issues such as strokes and heart attacks. Now,\u00a0<\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/37952131\/\"><span>new research<\/span><\/a><span> finds that semaglutide at the Wegovy dose (usually slightly higher than the Ozempic dose for diabetes) also has those benefits in those who don\u2019t have a diabetes diagnosis but do have obesity and cardiovascular disease.<\/span><\/p>\n<p><span>In a clinical trial sponsored by Novo Nordisk, the maker of Wegovy, half of more than 17,000 people with obesity were given semaglutide (Wegovy); the other half got a placebo. Compared to those on the placebo, those who took the Wegovy had a 20% reduction in strokes, heart attacks, and deaths from cardiovascular causes over a 33-month period.\u00a0<\/span><\/p>\n<\/section>\n<section><pagebreak\/>\n<p><span>The study results are a \u201cbig deal,\u201d Aronne said. The results make it clear that those with obesity but not diabetes will get the cardiovascular benefits from the treatment as well. While more analysis is necessary, he said the important point is that the study showed that reducing body weight is linked to improvement in critical health outcomes.<\/span><\/p>\n<p><span>As the research evolves, he said, it\u2019s going to be difficult for insurers to deny medications in the face of those findings, which promise reductions in long-term health care costs.<\/span><\/p>\n<p><span><strong>Insurance Coverage<\/strong><\/span><\/p>\n<p><span>In November, the American Medical Association voted to adopt a\u00a0<\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.ama-assn.org\/press-center\/press-releases\/ama-urges-insurance-coverage-parity-emerging-obesity-treatment-options\"><span>policy<\/span><\/a><span> to urge insurance coverage for evidence-based treatment for obesity, including the new obesity medications.<\/span><\/p>\n<p><span>\u201cNo single organization is going to be able to convince insurers and employers to cover this,\u201d Aronne said. \u201cBut I think a prominent organization like the AMA adding their voice to the rising chorus is going to help.\u201d<\/span><\/p>\n<p><span>Coverage of GLP-1 medications could nearly double in 2024, according to a\u00a0<\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/ir.accolade.com\/news-releases\/news-release-details\/glp-1-coverage-employer-plans-could-nearly-double-2024\"><span>survey<\/span><\/a><span> of 500 human resources decision-makers released in October by Accolade, a personalized health care advocacy and delivery company.\u00a0While 25% of respondents said they currently offered coverage when the survey was done in August and September, 43% said they intend to offer coverage in 2024.<\/span><\/p>\n<\/section>\n<\/div>\n<div data-page=\"4\">\n<section>\n<p><span>In an email, David Allen, a spokesperson for America\u2019s Health Insurance Plans, a health care industry association, said: \u201cEvery American deserves affordable coverage and high-quality care, and that includes coverage and care for evidence-based obesity treatments and therapies.\u201d<\/span><\/p>\n<p><span>He said \u201cclinical leaders and other experts at health insurance providers routinely review the evidence for all types of treatments, including treatments for obesity, and offer multiple options to patients \u2013 ranging from lifestyle changes and nutrition counseling, to surgical interventions, to prescription drugs.\u201d\u00a0<\/span><\/p>\n<p><span>Allen said the evidence that obesity drugs help with weight loss \u201cis still evolving.\u201d<\/span><\/p>\n<p><span>\u201cAnd some patients are experiencing bad effects related to these drugs such as vomiting and nausea, for example, and the likelihood of gaining the weight back when discontinuing the drugs,\u201d he said.\u00a0<\/span><\/p>\n<p><span>Others are fighting for Medicare coverage, while some experts contend the costs of that coverage would be overwhelming. A bipartisan bill, the\u00a0<\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.congress.gov\/bill\/118th-congress\/house-bill\/4818\"><span>Treat and Reduce<\/span><\/a><span> Obesity Act of 2023, would allow coverage under Medicare\u2019s prescription drug benefit for drugs used for the treatment of obesity or for weigh loss management for people who are overweight. Some say it\u2019s an uphill climb, citing a Vanderbilt University\u00a0<\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.nejm.org\/doi\/full\/10.1056\/NEJMp2300516\"><span>analysis<\/span><\/a><span> that found giving just 10% of Medicare-eligible patients the drugs would cost $13.6 billion to more than $26 billion.<\/span><\/p>\n<\/section>\n<section><pagebreak\/>\n<p><span>However, a\u00a0<\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/healthpolicy.usc.edu\/research\/benefits-of-medicare-coverage-for-weight-loss-drugs\/\"><span>white paper<\/span><\/a><span> from the University of Southern California concluded that the value to society of covering the drugs for Medicare recipients would equal nearly $1 trillion over 10 years, citing savings in hospitalizations and other health care costs.<\/span><\/p>\n<p><span>Comprehensive insurance coverage is needed, Apovian said. Private insurance plans, Medicare, and Medicaid must all realize the importance of covering what has been now shown to be life-saving drugs, she said.\u00a0<\/span><\/p>\n<p><span>Broader coverage might also reduce the number of patients getting obesity drugs from unreliable sources, in an effort to save money, and having adverse effects. The\u00a0<\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/www.fda.gov\/drugs\/postmarket-drug-safety-information-patients-and-providers\/medications-containing-semaglutide-marketed-type-2-diabetes-or-weight-loss\"><span>FDA warned against<\/span><\/a><span> counterfeit semaglutide in December.<\/span><\/p>\n<p><span><strong>Long-Term Picture<\/strong><\/span><\/p>\n<p><span>Research suggests the obesity medications must be taken continuously, at least for most people, to maintain the weight loss. In a\u00a0<\/span><a rel=\"nofollow noopener\" target=\"_blank\" href=\"https:\/\/jamanetwork.com\/journals\/jama\/fullarticle\/2812936\"><span>study<\/span><\/a><span> of patients on Zepbound, Aronne and colleagues found that withdrawing the medication led people to regain weight, while continuing it led to maintaining and even increasing the initial weight loss. While some may be able to use the medications only from time to time, \u201cthe majority will have to take these on a chronic basis,\u201d Aronne said.<\/span><\/p>\n<\/section>\n<\/div>\n<div data-page=\"5\">\n<section>\n<p><span>Obesity, like high blood pressure and other chronic conditions, needs continuous treatment, Apovian said. No one would suggest withdrawing blood pressure medications that stabilize blood pressure; the same should be true for the obesity drugs, she said.<\/span><\/p>\n<p><i><span>Apovian consults for FORM, the telehealth platform Lilly uses for LillyDirect, and consults for Novo Nordisk, which makes Saxenda and Wegovy. Aronne is a consultant and investigator for Novo Nordisk, Eli Lilly, and other companies.<\/span><\/i><\/p>\n<\/section>\n<\/div>\n<p>[ad_2]<br \/>\n<br \/><a href=\"https:\/\/www.webmd.com\/obesity\/news\/20240125\/eli-lilly-offers-obesity-drug-directly-to-consumers?src=RSS_PUBLIC\">Source link <\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>[ad_1] Jan. 5, 2024 \u2014 Eli Lilly, maker of the anti-obesity drug Zepbound, announced this week the launch of LillyDirect, a direct-to-patient portal, allowing some patients to obtain its drug&hellip;<\/p>\n","protected":false},"author":1,"featured_media":4736,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[38],"tags":[],"class_list":["post-4735","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-sexting"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.9 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Eli Lilly Offers Obesity Drug Directly to Consumers - 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