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May possibly 5, 2023 — The on-again, off-all over again saga of Wegovy provide difficulties for U.S. people searching to eliminate body weight is again.
Novo Nordisk, the organization that manufactures and markets semaglutide for fat decline as Wegovy and for dealing with sort 2 diabetes as Ozempic, introduced Thursday that the firm will only be equipped to “supply minimal portions of .25 mg, .5 mg, and 1 mg dose strengths [of Wegovy] to wholesalers for distribution to retail pharmacies” in the United States. This indicates that the expected provide “will not meet expected patient demand,” a problem the organization expects to go on “through September.”
The update added that the bottleneck is prompted by provide failing to satisfy U.S. need, despite the fact that the announcement also assured people now using the drug and using greater weekly dosages that their supply must not be influenced.
“We do not at this time foresee supply interruptions of the 1.7 mg and 2.4 mg dose strengths of Wegovy,” the announcement claimed.
Déjà Vu All In excess of Yet again
If this provide scarcity appears to be like déjà vu, that’s since the U.S. provide of Wegovy also fell shorter during much of 2022. Nevertheless, by December 2022 and as not long ago as February 2023, statements from Novo Nordisk made it seem like the provide shortages have been coming to an stop. The company’s announcement currently reveals that optimism was misplaced.
A lack of doses for .25 mg, .5 mg, and 1 mg will generally influence individuals starting up on Wegovy. To keep away from or lower side results, especially gastrointestinal consequences, when sufferers commence treatment with semaglutide or any other similar drug, they start off on the least expensive dose and steadily work up to a maintenance dose, which for Wegovy can be up to 2.4 mg/week.
The company’s announcement acknowledged this affect, indicating wellbeing care providers must “take into thought the constrained offer of the .25 mg, .5 mg and 1 mg dose strengths of Wegovy as part of their final decision-making when initiating new sufferers on therapy, recognizing the probability of disruption in care.”
Novo Nordisk’s announcement also urged companies and individuals to stay clear of employing the semaglutide formulation created for dealing with variety 2 diabetic issues, Ozempic, as a work-about. The statement highlighted that Wegovy and Ozempic “are not interchangeable.”
This Wegovy scarcity redux might prompt a return to the workarounds devised by U.S. weight decline clinics past yr.
One of these workarounds requires beginning clients on a distinct drug for bodyweight decline, such as liraglutide (Saxenda), and then crossing the affected individual about to an available, better-dose formulation of Wegovy the moment the early section is finish.
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